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Physiological Biochemistry

Dr. Jerome Garcia is a Professor of Biology & Title V STEM Activities Director.

Description:

  • Alzheimer’s Disease Model 
    • Hepatic LRP-1 plays an important role in amyloidosis in Alzheimer’s disease mice: Potential role in chronic heavy alcohol feeding 
    • Submitted to Alzheimer’s Research & Therapy on 15 March 2024
    • Modulation of hepatic amyloid precursor protein and lipoprotein receptor-related protein 1 by chronic alcohol intake: Potential link between liver steatosis and amyloid-β
  • Mitochondrial Dynamics Fish Model 
    • Hypersalinity drives physiological and morphological changes in Limia perugiae (Poeciliidae) 
    • Biology Open (2016) 5, 1093-1101 doi:10.1242/bio.017277 
  • Aging Model
    • Oxidative stress and protein post-translational modification ]
  • Lipoic Acid Model
    • Potential diet supplements for weight loss

Techniques used: 

  • Western Blots 
  • Mitochondria isolation 
  • Metabolics
  • Cell culture

Student Requirements:

  • Self motivated
  • Independent thinkers
  • Animal trained (WILL WORK WITH MICE!)