{"id":303,"date":"2020-08-26T16:24:54","date_gmt":"2020-08-26T23:24:54","guid":{"rendered":"https:\/\/artsci.laverne.edu\/biology\/?page_id=303"},"modified":"2024-06-24T10:53:21","modified_gmt":"2024-06-24T17:53:21","slug":"endocrine-disrupting-chemicals","status":"publish","type":"page","link":"https:\/\/artsci.laverne.edu\/biology\/endocrine-disrupting-chemicals\/","title":{"rendered":"Endocrine Disrupting Chemicals"},"content":{"rendered":"<p><a href=\"https:\/\/laverne.edu\/directory\/person\/christine-a-broussard\/\"><strong>Dr. Christine Broussard<\/strong><\/a> heads research in the area of Endocrine Disrupting Chemicals and T Cell development.\u00a0 She only accepts\/has 10 students at a time working on this project. She also heads research focused on Developmental Immunotoxicology and STEM Education Reform.<\/p>\n<p><strong>Description:<\/strong><\/p>\n<ul>\n<li>Determine the mechanism by which endocrine-disrupting chemicals affect the development of the immune system\n<ul>\n<li>\u2013EDCs are ubiquitous\n<ul>\n<li>Plastics \u2013 BPA<\/li>\n<li>Medication \u2013 DEC<\/li>\n<li>Pesticides \u2013 MXC<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li>Use mice and cell lines (mouse\/human)<\/li>\n<\/ul>\n<p><strong>Techniques used:<\/strong><\/p>\n<ul>\n<li>Tissue culture<\/li>\n<li>In vitro differentiation of thymocytes<\/li>\n<li>Flow cytometry and fluorescence microscopy<\/li>\n<li>Western blot<\/li>\n<li>PCR<\/li>\n<li>Embryo dissection<\/li>\n<li>Large data set analysis<\/li>\n<li>Cell Biology and Immunology<\/li>\n<li>Immunophenotyping &amp; flow cytometry<\/li>\n<li>Tissue Culture<\/li>\n<li>CURE curriculum design<\/li>\n<\/ul>\n<p><strong>Student Requirements:<\/strong><\/p>\n<ul>\n<li>Completion of BIOL 345 Immunology by the end of junior year.<\/li>\n<li>Juniors and seniors have specific \u201clab jobs\u201d<\/li>\n<li>Hands-on to help students move along the project<\/li>\n<li>Be self-motivated and enthusiastic<\/li>\n<li>Need to work in teams and be reliable!<\/li>\n<\/ul>\n<p><strong>Past Research:\u00a0<\/strong><\/p>\n<ul>\n<li>BIOL 345 &#8211; Immunology<\/li>\n<\/ul>\n<p style=\"padding-left: 40px\">Developmental Immunotoxicology<\/p>\n<p style=\"padding-left: 40px\">Lucie Leung-Gurung*, Priscilla Escalante Cobb*, Faraj Mourad*, Cristina Zambrano*, Zachary Muscato*, Victoria Sanchez*, Kanya Godde &amp; Christine Broussard (2018).\u00a0<strong>Methoxychlor metabolite HPTE alters viability and differentiation of embryonic thymocytes from C57BL\/6 mice<\/strong>,\u00a0<em>Journal of Immunotoxicology<\/em>, 15:1, 104-118, DOI:10.1080\/1547691X.2018.1474978<\/p>\n<p style=\"padding-left: 40px\">*La&nbsp;Verne students<\/p>\n<p style=\"padding-left: 40px\">Eddie Avellaneda*, Atalie Lim*, Sara Moeller*, Jacqueline Marquez*, Priscilla Escalante Cobb*, Cristina Zambrano*, Aaditya Patel, Victoria Sanchez*, K. Godde, and Christina Broussard. (2021).\u00a0<strong>HPTE-Induced Embryonic Thymocyte Dath and Exacerbated by Concurrent TCR Signaling<\/strong>.\u00a0<em>International Journal of Molecular Sciences<\/em>, 22(18), 10138.<\/p>\n<p style=\"padding-left: 40px\">*La&nbsp;Verne students<\/p>\n<ul>\n<li>STEM Education Transformation<\/li>\n<\/ul>\n<p style=\"padding-left: 40px\">Broussard, Christine, Margaret Gough Courtney, Sarah Dunn, K. Godde, and Vanessa Preisler.\u00a0<strong>&#8220;Course-based undergraduate research experiences performance following the transition to remote learning during the COVID-19 pandemic.&#8221;\u00a0<\/strong><em>Journal of College Science Teaching<\/em> 51, no. 1 (2021): 27-41.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Christine Broussard heads research in the area of Endocrine Disrupting Chemicals and T Cell development.\u00a0 She only accepts\/has 10 students at a time working on this project. She also heads research focused on Developmental Immunotoxicology and STEM Education Reform. Description: Determine the mechanism by which endocrine-disrupting chemicals affect the development of the immune system [&hellip;]<\/p>\n","protected":false},"author":69,"featured_media":375,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-landing-page.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-303","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v23.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Endocrine Disrupting Chemicals | Biology | University of La Verne<\/title>\n<meta name=\"description\" content=\"Determine the mechanism by which endocrine-disrupting chemicals affect the development of the immune system. 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